Search / 28 posts tagged tnf

Image via Wikipedia Patients with Rheumatoid Arthritis should benefit from the new range of drugs called Tumour Necrotic Factor Inhibitors (Anti-TNF). Tests on three of these new drugs slowed progression and reduced symptoms by up to 50%.

“Tumor necrosis factor (TNF) is known to play an important role in various immune-mediated ocular diseases; intravenous administration of the anti-TNF monoclonal antibody infliximab has proved beneficial in such cases.”1 Eye surgeons and researchers from “Attikon” University Hospital, University

Do you have arthritis? If so you are not alone. 66,000,000 people do almost 1 in 3 adults. Arthritis is second only to heart disease as a cause of work disability.

New research suggests that Enbrel, Remicade, Humira and other biologic TNF-blockers widely used to treat rheumatoid arthritis do not appear to cause cancer, which has been a concern associated with the drugs. Researchers from the Spanish Foundation of Rheumatology presented data at the American College of Rheumatology’s annual meeting in San Francisco this week.

Biologic therapy has revolutionized our approach to the treatment of rheumatoid arthritis (RA). Less than 10 years ago, the best we could hope for was to “modify disease” or slow it down and also help with symptoms. Now the goal is to not only control symptoms, it is to get RA into complete remission.

Washington, Oct 7 (ANI): Researchers at the University of Missouri have identified the proteins that play important roles in blood-vessel dysfunction in type 2 diabetes. Previous studies have shown that cardiac function is compromised and cardiovascular diseases are increased in people with type 2 diabetes.

A 2007 federal law requires the FDA to disclose all its investigations into reports of possibly drug-related adverse events. The first of this series of quarterly reports has been released. It includes adverse events reported between January 1 and March 31, 2008.

ESBATech AG has announced successful completion of a clinical study for “Lead Antibody Fragment in Ophthalmic Indications”. “ESBA105 is a single-chain antibody fragment directed against TNF-alpha, and it is being developed initially for ophthalmic indications.” More information from a Release

The FDA has issued an alert to healthcare providers about the risk of a serious fungal infection which may develop in users of rheumatoid arthritis drugs Remicade, Humira, Enbrel and Cimzia. The agency indicates that new information will be added to the drugs’ black box warnings about the risk.

FDA ALERT The U.S. Food and Drug Administration today announced that the manufacturers of Humira, Cimzia, Enbrel, and Remicade must strengthen the existing warnings, in the Warnings and Precaution sections of the drugs’ prescribing information and Medication Guides, on the risk of developing opportunistic fungal infections.